By Gerhard Nahler (auth.)
This dictionary contains quite a few phrases generally utilized in pharmaceutical drugs. The third version underlines the expanding value of this technological know-how and the altering regulatory surroundings, specially concentrating on the examine and improvement of latest treatments in addition to on carrying out scientific trials, advertising authorizations for brand spanking new medicinal items, and defense features together with pharmacovigilance. The variety of keyword phrases has been significantly enlarged and is followed by way of an up to the moment checklist of an important web pages. just like the former variations, this new booklet explains approximately 1,000 abbreviations most ordinarily utilized in pharmaceutical medication. This quantity might be a useful software for pros operating within the pharmaceutical undefined, scientific and preclinical study, regulatory affairs, advertising and marketing and advertising authorization of pharmaceuticals.
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Extra info for Dictionary of Pharmaceutical Medicine
C cachexia def. unintended and progressive weight loss that is often accompanied by weakness, fever, nutritional deficiencies, diarrhoea, and usually with a disproportionate muscle wasting. It occurs in many chronic illnesses and diseases such as cancer, in particular advanced stage cancer, but also Alzheimer’s disease, chronic heart failure, chronic lung disease, congestive heart failure, cystic fibrosis, Crohn’s disease, renal failure, rheumatoid arthritis, tuberculosis, liver cirrhosis, heart surgery, sepsis and sarcopenia; there is no universally accepted definition but the 95 % CIs for change in body weight in healthy adults is ±2 % in 1 month and ±5 % in 6 months; see weight.
Diagnosis or treatments in cancer); allocation b. = even drugs of the same substance class and being nearly identical may not be “allocated” by prescribing physicians in exactly the same way, new drugs are more likely to find their principle first uses in patients who have not responded satisfactorily to previously available drugs; attrition b. = biased occurrence and handling of protocol deviations and losses to follow-up; depletion b. = patients not tolerating or not responding to a treatment leave the study; changing pattern b.
Clinical trial authorisation (CTA) Formal approval to do studies; in most countries formal approval by health authorities to do studies esp. g. g. ; see also clinical trial certificate, clinical trial database, clinical trial exemption, EudraCT. clinical trial certificate (CTC) Formal approval to do studies in the UK; valid for 2 years, renewable; see also clinical trial authorisation, clinical trial exemption. clinical trial compensation guidelines Guidelines produced by the ABPI; according to which compensation should be paid when the injury was attributable to the medicinal product or any procedure provided for by the protocol, for the more serious injury of an enduring and disabling character (not for temporary pain or discomfort), for injuries caused by procedures adopted to deal with adverse reactions to a product under trial, regardless of whether the reaction was foreseeable or predictable or whether the patient is able to prove negligence of the company; see also insurance.